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Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP+-induced dopaminergic neuronal cell death: Role of caspases, ROS, and JNK

GHK-Cu has also been examined for its influence on inflammatory mediators and cellular stress signaling

Although the BBB excludes many drugs, brain capillary endothelial cells express transporters and receptors that selectively import essential nutrients (e.g., insulin receptor, transferrin receptor, glucose transporter-1) [51]