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Patients can experience reduced cravings, improved insulin sensitivity, and gradual, sustainable weight loss when combined with a balanced diet and regular physical activity

Proton pump inhibitors, H2-receptor antagonists, metformin, and vitamin B-12 deficiency: Clinical implications

It is not scheduled under the Controlled Substances Act, but products marketed as "MK-677" capsules or powders are unapproved drugs under FDA rules, and in practice it is sold almost exclusively online as an unregulated "research chemical" labeled not for human consumption

[1] Because the vial contains benzyl alcohol as a preservative, it is contraindicated in neonates and infants