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Practical implementation involves decisions about administration, sourcing, monitoring, and professional guidance that determine whether a research protocol produces useful data or wasted time and money

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References Wharton S, Blevins T, Chen L, et al

According to OBRA, the use of antidiabetic medications should include monitoring (e.g., periodic blood glucose) for effectiveness based on desired goals for that individual and to identify complications of treatment such as hypoglycemia or impaired renal function