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doi:10.2147/ijgm.S318949 Nguyen TT, Woo HJ, Kang HK, et al

Prime has developed a universal lipid nanoparticle (LNP) targeted to deliver LNP-RNA Prime Editors (PEs) to the liver by a single intravenous (IV) infusion

Additional post-translational modifications encompassed by the invention include, for example, e.g., N-linked or O-linked carbohydrate chains, processing of N-terminal or C-terminal ends), attachment of chemical moieties to the amino acid backbone, chemical modifications of N-linked or O-linked carbohydrate chains, and addition or deletion of an N-terminal methionine residue as a result of prokaryotic host cell expression

We began auditing the Worksheet S-10 data for selected hospitals in the Fall of 2018 so that the audited uncompensated care data from these hospitals would be available in time for use in the FY 2020 IPPS/LTCH PPS proposed rule