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the putatively Neanderthal Val92Met variant of the MC1R gene, which may be weakly associated with red hair and UV radiation sensitivity, [156] is primarily found in East Asian, rather than European, individuals

Pathophysiology beyond dopaminergic neuronal loss The alpha-synuclein model Alpha-synuclein is a presynaptic neuronal protein whose abnormal aggregation into Lewy bodies leads to disruption in cellular homeostasis and consequently neurodegeneration 7

The peptide successfully heals internal fistulas (gastrocutaneous, duodenocutaneous, and colocutaneous) in experimental models, achieving fistula closure even when treatment is delayed for one month after fistula formation

Repeated exposure to low doses can lead to chronic liver disease and cirrhosis