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59,60 Specific genes implicated include vascular endothelial growth factor (VEGF), neurotrophic receptor tyrosine kinase 1, sodium voltage-gated channel alpha subunit 2 (SCN2A), angiotensin-converting enzyme, and methylenetetrahydrofolate reductase, with polymorphisms associated with increased DN susceptibility

The timeline varies depending on injury severity

Vitamin deficiencies are supposed to be a thing of the past

If no, because the injury is spread across multiple locations, because inflammation is the primary barrier rather than tissue damage at one spot, or because the patient is post-surgical and every affected area cannot be injected individually, TB-500 addresses the problem at the systemic level that BPC-157 cannot reach