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More targeted CNS uptake has been attempted by conjugating polymeric nanoparticles with ligands like transferrin or lactoferrin (Zha et al., 2024

Additionally, GHK-Cu increases the expression of lysyl oxidase, the enzyme responsible for cross-linking collagen and elastin fibers, thereby reinforcing the three-dimensional architecture of the extracellular matrix

This formulation utilizes three ways to support glutathioneintracellular with SAG, intracellular biosynthesis with NAC, and extra/intracellular (systemic) support with GSH.* Moreover, the liposomal S-acetyl L-glutathione in this formula provides a double layer (acetylation + liposomes) of protection to the glutathione molecule, further supporting its intracellular bioavailability.*

Research Findings The research foundation for Epithalon is substantial, though much of this work has been conducted in Russia and published primarily in Russian or Eastern European journals, with less representation in mainstream Western scientific literature