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ASXL1 1-645 but not ASXL1 1-591 concurrently associates with BRD4 and MLL3/4 We have previously shown that the amino acid sequence of ASXL1 (aa 607-627) serves as a binding site for the second and third PHD fingers of methyltransferases MLL3 and MLL4, denoted as MBH (MLL binding helix, ASXL1 MBH ) 10,38

doi: 10.1016/s0092-8674(00)81674-8 23 BrerS

24 h after the treatment, cells were fixed with 10% trichloroacetic acid, extensively washed, then incubated with the dye, washed and finally resolubilized in 10 mM Tris base, prior to scanning the plates at 565 and 690 nm (main signal and background, respectively)

What's the difference between glutathione and L-glutamine