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Peripheral smears characteristically show small, mature-appearing lymphocytes and fragile smudge cells

LuLYangLKYueJWangXSQiJYYangFet alScutellarin alleviates depression-like behaviors induced by LPS in mice partially through inhibition of astrocyte-mediated neuroinflammation

Additionally, it down-regulates the Wnt/ -catenin signaling pathway, a key regulator of autophagy, and prevents EMT in renal cell carcinoma (786-O and ACHN) and liver cancer (Hep G2) cells [909, 910]

It is also noteworthy that the k cat of the two enzymes also differ by 3-fold, something that we cannot explain using static structures and may involve distinctions in active site motion, as outlined elegantly for other enzyme systems 30