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These findings align with global analyses from Europe, North America, and Asia reporting similar population-level increases in vitamin B12 deficiency, where prevalence ranges from 5 to 20% depending on age, diet, and socioeconomic status

Here, we will review the structural features of pathogenic and functional amyloid fibrils, which rely within their pathological or biological cycles on the prion principle, and how SSNMR data can be used to obtain structural models of such fibrils

She had no significant medical history and was afebrile