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USA 107 , 26692674 (2010)

Cancer Res (2011) 71(13):458597

discovered that oestrogen-activated GPER in CAFs promotes the expression of GLUL and lactate dehydrogenase B (LDHB), enhances the survival of Triple Negative Breast Cancer(TNBC) cells both in vitro and ex vivo, and increases chemotherapy resistance [130]