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Langmuir 23:15181522

Results FGF21 knockout exacerbates neural apoptosis and brain edema, increases lesion volume, and worsens neurological deficits following TBI

It, thus, appears that these interventions do not counteract specific aspects of the pathophysiology of the individual movement disorders, but non-specifically replace and block abnormal activity in the basal ganglia networks that target the relatively intact downstream portions of the motor circuitry [294,295,296]