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Because GHK is a naturally occurring peptide already present in human plasma, serum, saliva, and urine, the body recognizes it as endogenous rather than foreign

Decreased transcription of ChREBP-/ isoforms in abdominal subcutaneous adipose tissue of obese adolescents with prediabetes or early type 2 diabetes: associations with insulin resistance and hyperglycemia

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Another common use is as an adjunct in managing neuropathy due to diabetes or medication effects, when a clinician identifies or suspects a coexisting deficiency