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SOD1 has been postulated to localize to the outer mitochondrial membrane (OMM), where superoxide anions would be generated, or the intermembrane space

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Chem 405 (2013) 58335841

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In contrast, Y390 largely maintained the conformation observed in the cryo-EM structure when in the presence of NSD2, with nearly no change in the distance to C326 (Supplementary Fig

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