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Description

Unlike traditional apoptosis, apoptosis is characterized by plasma membrane blebbing, pseudopod retraction, reduction of cellular and nuclear volume, formation of apoptotic bodies and nuclear fragmentation, and chromatin condensation

148 ReygaertW

However, both of these processes require the active form of folate, methylfolate

This review highlights that given the robust preclinical evidence and high public interest, there is a critical need for well-designed human trials to assess the safety, efficacy, and clinical utility of BPC-157 in musculoskeletal medicine