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Visible physical changes (body composition, skin texture) appear at 8-12 weeks

A pilot trial on the efficacy of interpersonal social rhythm therapy with quetiapine or placebo in patients experiencing bipolar depression reported that the quetiapine group had higher pro-inflammatory and lower anti-inflammatory cytokines compared to the placebo group [80]

10.3109/09513590.2015.1101444 71 PetersonS

Peng DF, Hu TL, Schneider BG et al (2012) Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas