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(Luo et al., 2022) addressed this by using ECM-modified hydrogels (ECM-Gels) to load cartilage endplate stem cells (CESCs) overexpressing sphingosine kinase 2 (Sphk2)

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By clearing out senescent cells, FOXO4-DRI decreases the production of inflammatory signals, promotes tissue repair, and restores a healthier cellular environment, effectively reducing chronic inflammation and its negative effects on the body (7)

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Whatever the cause of your dark circles, Eye Plastic Surgery of Minnesota can help you to create a treatment plan that addresses your concerns.

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