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BCL6 is regulated by IL6/STAT3 signaling and miRNAs, integrating inflammatory and epigenetic mechanisms ( 2.5 Microbiome and metabolic influences Emerging evidence highlights the intricate roles of reproductive tract and gut microbiome dysbiosis, alongside metabolic and coagulation system perturbations, in the pathogenesis of endometriosis and associated infertility

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The suppressive impact of 3-oxoLCA on Th17 cells was facilitated by ROR t inhibition, whereas isoalloLCA boosted Treg cells by increasing mitochondrial reactive oxygen species production and enhancing FOXP3 + expression through the intronic enhancer conserved noncoding sequence (CNS)