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A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder

Eneroth H, El Arifeen, S, Persson LA, et al

In general, the interaction between oxidative stress and neurotransmitter alterations is a key factor to consider in the pathophysiology of depression

Most striking, IAPP toxic oligomers appear to disrupt membranes of the secretory pathway, and then when adjacent to mitochondria, disrupt mitochondrial membranes ( Figure 4 illustrates schematically the process by which Akkermansia spp protect the host from type II diabetes