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SAMe is the universal methyl donor and is used for DNA methylation and to make phospholipid membranes, choline, sphingomyelin, acetylcholine, and other neurotransmitters

Notably, with the increasing incidence and the trend of younger onset of breast cancer, a growing number of young patients were developing the POI after CTX chemotherapy 16,17,18

This is particularly true for therapeutic or deficiency-specific supplements, where precise doses are crucial for managing conditions or correcting deficiencies

Roughly below the MLD (approximately 150 m), the assimilation of additional surface drifter observations results in larger RMSEs than when assimilating only the temperature and salinity profiles