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This reduced activity may impair redox homeostasis, particularly under conditions of OS (Tang et al., 2008

4.2.2 Tyrosine and phenylalanine metabolism 4.2.2.1 Production and hazards of p-cresyl sulfate (pCS) p-Cresyl sulfate (pCS) is another important protein-bound uremic toxin, formed from p-cresol produced by anaerobic bacterial degradation of tyrosine and phenylalanine through hepatic sulfation or glucuronidation (122)