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however, it caught up to controls at ZT16, surprisingly gaining rhythmicity in cKOt mice (Figure 7, A and C)

Among these pathways, glycolysis is the main metabolic pathway in the majority of PDAs 8

APS may phosphorylate IRS-1 by the phosphatidylinositol-3 kinase (PI3K)/protein kinase B (PKB, also known as Akt) signal pathway to promote the activation of the AMPK/acetyl-CoA carboxylase (ACC) pathway and its downstream targets, glycogen synthase kinase 3beta (GSK3), phosphoenolpyruvate carboxyl kinase (PEPCK), and gluconeogenic enzymes glucose 6-phosphatase (G6Pase) phosphorylation, to improve glucose metabolism (Sun et al., 2019)

Under stressful conditions, exogenous GSH treatment significantly improved the development characteristics of sunflower and chickpea plants chloroplasts and, consequently, photosynthetic pigments [59]