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Ko et al., 2018)

Tesamorelin's Phase 3 trials and Sermorelin's original approval studies were built around HIV-associated lipodystrophy and pediatric growth failure, not muscle building, so their bodybuilding use rests on extrapolation rather than direct testing

Once-weekly cagrilintide, a long-acting amylin analog that is non-selective for the CTRs and amylin receptors, has shown promising weight-loss effects as well as improvement in cardiometabolic factors