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Angiogenesis promotes the formation of new blood vessels, which will aid the delivery of oxygen and nutrition to the damaged tissue

The absorbance was measured at 450 nm using an enzyme marker (BioTek, Gen 5), and the growth rate of cells was calculated as follows: where A blank is the absorbance of the wells without cells, and A control and A test are the absorbances of the control and treated cells, respectively

Targeting the key factor VEGFR2 promotes tumor vascular normalization, thus increasing immune cell infiltration and activation