macula melanotica bucal Mácula melanótica labial: diagnóstico, diferenciais e condutas clínicas Mácula melanótica oral.

C4a also induces the generation of reactive oxygen species (ROS) via NADPH oxidase, contributing to oxidative stress, mitochondrial dysfunction, and downstream redox-sensitive signaling cascades such as NF-B and AP-1

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Cells were washed to remove detached cells, stained with a live cell dye (Molecular Probes R37609) and then subjected to fluorescent imaging using an EVOS system and Image J for quantification

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