In 2012, CBS was first identified as an epigenetic biomarker for the molecular diagnosis of gastrointestinal cancers, sparking interest in its role in GC
It was required to incorporate dose less than or equal to 20 mg per patch and still deliver at least sufficient amount at the end of 24 hrs considering half-life of around or less than 2 hrs

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22 Molecular modeling using Schrdinger Maestro further confirmed these findings, providing deeper insights into the binding interactions between Osimertinib, CP-24, and DDRGK1