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Highly recomm

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

In 51 patients, SNP was given for short periods, while in 19 patients, SNP was given over longer periods of up to 2 weeks, usually in combination with sodium thiosulfate infusion

Twice-daily dosing (500mcg morning and evening) shows up in more aggressive protocols but adds cost and injection logistics on top of an already-active TRT schedule