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Although extension of habitual short sleep did not show to significantly counterbalance the immune consequence of sleep deprivation 286,287,288 , mixed results derive from nighttime recovery sleep following sleep deprivation (Table 1), with limited evidence of effectiveness for specific immune parameters 210,214 , and mostly after multiple consecutive nights of 8 h sleep recovery or with an extended nocturnal sleep duration 212,289

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Cerebrospinal fluid-contacting neurons (CSF-cNs) located in the ependyma have bidirectional communication function between cerebralspinal fluid and brain parenchyma, and may participate in the pathway of iron-induced cognitive dysfunction through projected nerve fibers and transmitted factor, such as 5-hydroxytryptamine, etc

7: Andersen NB, Malmlf K, Johansen PB, Andreassen TT, rtoft G, Oxlund H