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At the B-cell level, these serologic findings are paralleled by a significantly decreased frequency of circulating B cells as part of general lymphopenia but a substantial expansion of PBs, accounting for up to 30% of B cells upon acute infection [131,132,133,134]

"It's maddening," said Timothy Caulfield, a professor in the faculty of law and the school of public health and research director of the Health Law Institute at the University of Alberta

The placement of the catheter and application of OHCbl infusions are readily accomplished by the parents at home and well tolerated by the patient

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