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Description

AD is a complex, progressive neurodegenerative disorder characterized by cognitive decline, amyloid-beta (A) plaques, and tau protein neurofibrillary tangles

10.1016/bs.ircmb.2019.11.005 120 PistoiaF.SaccoS.DeganD.TiseoC.OrnelloR.CaroleiA

This is clear from both the limited reductions in prevalence achieved over the past decade, and also from the health economic modelling predictions we summarise here