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Nevertheless, genetic variation only explains a minor part of interindividual variability, suggesting regulation by nuclear receptors, PAPS-cofactor availability and inhibition by various drugs and environmental compounds could be major determinants of variability in SULT activity 15

In this study, we investigated the skin toxicity of several copper compounds using cell-based in vitro tests and evaluated the expression of various cytokines at genomic and proteomic levels to discover irritancy biomarkers suitable for copper compounds

Recent studies have also evaluated the clinical utility of DNA methylation hotspots as prognostic biomarkers for BLCA