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Prevention of Major Birth Defects : Expectant mothers with B12 deficiency may choose to receive injections to ensure their levels are sufficient, contributing to the health of their unborn child

Despite these advantages, GSH/GSSG is not well suited as a plasma biomarker of oxidative stress due to the low plasma concentrations of GSH species, which are usually in the low micromolar range, and the low sensitivity of the assays

400,401 UPS-targeted therapies in NDDs Proteasome activation The ubiquitinproteasome system plays a central role in clearing misfolded and damaged proteins, and its dysfunction contributes directly to protein aggregation in NDDs

Pevec et al