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Description

Some foods may enhance berberine's absorption and effects

Their dual mechanismsmicrobiota regulation and barrier enhancementinclude stimulation of beneficial bacteria such as Lactobacillus and Bifidobacterium , elevation of SCFA production (e.g., butyrate as an epithelial energy source, acetate for Treg differentiation), inhibition of TLR4/NF-B inflammatory signaling, and activation of the Nrf2/HO-1 antioxidant pathway