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Black Spot on Lip: What Does It Mean? Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Venous Lake of Lip and Lip Freckle Removal with Iridex Laser
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