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After oral administration, triptans need to be absorbed from the gastrointestinal tract to reach the blood circulation and have to cross the bloodbrain barrier to get to the CNS

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Figure 3 displays SULT expression pies of the most important human cytosolic transferases in human tissues

The observed differences in resistance induction between MSNs-ss-SA and the other treatments could be explained as follows: (1) MSNs-ss-NH 2 grafted with SA via amide bonds could control the releases of SA under the action of rice-specific amidase, thereby extending its retention time in rice [78]