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In pursuit of this objective, it is essential to conduct multiplex, transcriptomics and other panomics (genomics, metagenomics, lipidomics, and metabolomics) investigations that provide comprehensive insights into cytokines, chemokines, growth factors, O&NS, atherogenicity profiles, and intracellular networks rather than focusing solely on a few biomarkers, such as CRP, IL-6, TNF-, and triglycerides