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[12] Lastly, ALA may have mild anticoagulant effects (by enhancing blood flow and endothelial function), so combining it with anticoagulant or antiplatelet drugs could very slightly increase bleeding tendency

The biochemical pathway involved with the metabolism of methionine to form S-Adenosylmethionine, homocysteine and the continuation of the cycle to form other biochemicals plays a central role in the metabolism of all mammalian cells

91 In UC patients, endoplasmic reticulum function may be impaired, leading to abnormal accumulation of intracellular proteins and exacerbation of the cellular inflammatory response

Indeed NSAIDs, by virtue of their renown anti-inflammatory and antiplatelet (especially aspirin) activities could be beneficial for both the early control of inflammation and the prevention of thromboembolism, thus theoretically limiting COVID-19 progression in a bimodal pattern