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For example, this center approved Modernas Spikevax, a messenger RNA vaccine designed to prevent COVID-19, in January 2022.

Sharma and Dietz, 2006

One of the considered mechanisms of migraine pathogenesis concerns the involvement of tumor necrosis factor (TNF-), which results in the occurrence of migraine symptoms through initiation of neuronal hyper-excitability, stimulation of nociceptors, and prostanoid production which, in turn, leads to initiation of neuroinflammation [69]