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An increased ROS load with unaugmented Gpx/GR ratio was also modelled to demonstrate the behaviour of a system that did not have higher Gpx concentration compared with GR, as would occur without introduction of our plasmid containing the enzymes in series

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Wong CYJ, Baldelli A, Hoyos CM et al (2024) Insulin delivery to the brain via the nasal route: unraveling the potential for Alzheimers disease therapy