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PMID 20628086.

CPD, 2011

BI-1 (BAX-1 inhibitor), a pro-survival PCD gene involved in the regulation of PCD pathways, was shown to reduce ROS accumulation in vertebrates and to activate Nrf2, which is a transcription factor of various antioxidants, including glutathione reductase (42, 64)

590 Diabetic retinopathy is also closely associated with DPN, with shared risk factors, such as poor glycemic control, hypertension, and dyslipidemia contributing to the development of both microvascular complications