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(PubMed) Kabat GC, Kim MY, Wactawski-Wende J, Shikany JM, Vitolins MZ, Rohan TE

The transdermal composition of claim 2 which sustains in an animal at least 50 % of plasma levels of GHK-Cu or copper tripeptide of maximum plasma concentration for at least 24 hrs

Moving from 0.5% to 1%, or from 1% to 2%, represents appropriate steps