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Oken BS, Kishiyama S, Zajdel D, et al

Figure 2 The core characteristics and mechanisms of candidalysin are well-defined: it exerts cytotoxicity by membrane insertion/lytication, activates pathways such as EGFR-MAPK and NLRP3 inflammasome to induce inflammation and damage in host cells, and targeted anti-infection strategies against this toxin have been summarized (Lortal et al., 2025)

Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice

Genome-wide gene expression profiling experiments have revealed that a wide array of genes (stress-responsive gene, heat-shock proteins, metallothioniens, sulfate-metabolizing proteins and assimilation pathway) are differentially expressed during As stress in rice plant 17