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Jitrapakdee S, Wallace JC (1999) Structure, function and regulation of pyruvate carboxylase

Modulation of TCA cycle activity may provide Staphylococcus with a survival advantage during infection ( Staphylococcus and its host ( Staphylococcus may exert its virulence effects by modulating the activity of the TCA cycle, ultimately contributing to the development of psoriatic skin lesions

It was early reported that HIF-1 is upregulated through SUMO1 modification at K391 and K477 residues, which may stabilize HIF-1 and enhance its transcriptional activity [185]