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Conclusion Although glutathione is able to coordinate heme bound iron, forming GShematin, the affinity of glutathione for hematin is such that any heme or hematin generated in the cytoplasm will be almost totally bound to glutathione, forming a 1:1 complex

doi: 10.1016/j.jhazmat.2023.131228 249 YangL.WenK.RuanX.ZhaoY.WeiF.WangQ

The molecular targets and therapeutic uses of curcumin in health and disease , 105-125

This extended window requires meticulous sterile handling, minimal needle punctures of the septum, and unwavering refrigeration at the correct temperature range