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5) Irisflorentin blocks erastin/RSL3-induced ferroptosis and TGF-1-stimulated fibrosis in primary tubular cells and suppresses Smad3 phosphorylation/Nox4 to reduce UUO-induced injury and fibrosis (202)

She completed her General Surgery residency at the University of Pittsburgh Medical Center (UPMC) where she served as Administrative Chief Resident, then remained at UPMC to complete a fellowship in Complex Surgical Oncology, during which she again served as Administrative Chief Fellow.[1] Following the completion of her fellowship training, Dr

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In tumor cells, MYC-driven glutamine metabolism promotes tumor growth, drug resistance and immune escape [48], whereas MYC-regulated glutamine metabolism in immune cells supports the activation, proliferation and cytokine secretion of effector T cells and NK cells and enhances the immune response and other immune functions [49]