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doi: 10.1038/nrm3013

The standard approach often begins with a low dose of semaglutide, commonly 0.25 mg weekly for the first four weeks, which serves primarily as an initiation dose to allow physiological adaptation rather than providing significant therapeutic effect

Usage in Pregnancy Since adequate human reproduction studies have not been done with corticosteroids, use of these drugs in pregnancy, nursing mothers or women of childbearing potential requires that the possible benefits of the drug be weighed against the potential hazards to the mother and embryo or fetus