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10.1016/j.nbd.2011.12.025 70 LoewenJ

Astaxanthin supports the system by regulating inflammation

On the other hand, p53 inhibits ferroptosis by inhibiting the activity of dipeptidyl peptidase 4 (DPP4) or inducing the expression of cyclin-dependent kinase inhibitor 1A (CDKN1A/p21) [77], both indicate the importance of p53 as a regulator of metabolism-related genes in ferroptosis (Fig