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Both stress-induced changes and direct alterations in peripheral nociceptive pathways have been implicated in pain modulation in IBS-C, with limited data available for FC

LC-MS/MS can distinguish GSH and GSSG through analyte-specific transitions and quantify them simultaneously or in parallel

Current therapies primarily address symptoms and have notable limitations, underscoring the need for alternative approaches, including lifestyle-based interventions

Potential therapeutic effects of cyanidin-3-O-glucoside on rheumatoid arthritis by relieving inhibition of CD38+ NK cells on Treg cell differentiation