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Of the ZEPBOUND-treated patients in OSA clinical studies, 37.2% and 19.5% of patients developed antibodies that were cross reactive to native GIP and native GLP-1, respectively

One possibility is that supplementary vitamin B-12 was preferentially shunted to fetal tissues and therefore did not result in improved maternal vitamin B-12 status

The most frequently reported are gastrointestinal: Nausea - very common (affects more than 1 in 10 people), typically most pronounced after dose increases Vomiting Diarrhoea or constipation Abdominal discomfort or bloating These effects typically reduce over time as the body adjusts to the medication

Individual results may vary based on health status, lifestyle, and treatment frequency