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Virtanen JK, Hantunen S, Lamberg-Allardt C, et al

We approached the question of the potential relevance of NQO1 in superoxide scavenging in cells using an NQO1 transfected series of Chinese hamster ovary cells (Siegel et al., 2004)

Svitkin YV, Cheng YM, Chakraborty T, Presnyak V, John M, Sonenberg N

Additionally, ROS can also trigger other cell death events in lens epithelial cells, such as apoptosis characterized by upregulation of the pro-apoptotic Bcl-2-associated X protein ( BAX ) gene and downregulation of the anti-apoptotic B-cell lymphoma-2 ( BCL-2 ) gene [30] as well as pyroptosis mediated by ROS-induced activation of the NLRP3 inflammasome/caspase 1/gasdermin D pathway [31]